Working principle of centrifuge

Release Date:

2025-05-16 15:08

Working principle of centrifuge

A centrifuge is a machine that uses centrifugal force to separate components in a mixture of liquid and solid particles, or liquid and liquid.

Design principle of medical centrifuges: Utilizing the centrifugal field force generated by the rotating rotor to accelerate the sedimentation speed of sample particles, thereby separating substances with different sedimentation coefficients or buoyant density differences in the sample.

The factors determining the magnitude of centrifugal force mainly include rotational speed (Revolved per minute, r/min) and centrifugal (rotor) radius, which are related to the forces (gravity, buoyancy, friction) acting on particles during rotational movement. Since the direction of centrifugal force is perpendicular to gravity, relative centrifugal force (Relative centrifugal force, denoted as rcf) is often used. Centrifugal force is one of the most important parameters for measuring a centrifuge and also one of the distinguishing standards for centrifuge classification. Centrifuges are typically provided with their maximum speed and centrifugal force upon leaving the factory. The rotor radius and sample mass remain constant during operation, only the rotational speed can be changed through control. Therefore, we often use rotational speed to describe a centrifuge, such as high-speed centrifuges, ultra-high-speed centrifuges, etc.